This article was made possible thanks to on-site reporting by Sasha Mbilika.
Last week, more than 250 professionals in the psychedelics space gathered at London’s Conway Hall for the third edition of PSYCH Symposium.
Researchers, regulators, investors and thought leaders gathered to discuss the past, present and future of psychedelic medicine in the UK and abroad.
Prof. David Nutt: The Harm of Psychedelics Has Been “Grossly Exaggerated”

Opening Remarks were given by Professor David Nutt, founder of Drug Science, the organisation that partnered with Prohibition Partners in hosting the Symposium.
Nutt shared a quote by Lord Dick Tavern, who has been a major influence in maintaining a sensible public dialogue about science, leading the charity Sense about Science to become the first patron of Drug Science.
Nutt shared a quote from Lord Tavern: “It may take time, but in a democracy, those who base their case on strong evidence and are prepared to argue for it with conviction are likely to prevail in the end. The sensible policy on the use of drugs is not a hopeless cause”
Nutt said the quote echoes optimism for industry progress and highlights Drug Science’s ongoing role in the field as it recovers from the 1971 UN Convention that banned classic psychedelics worldwide.
Nutt reported that potentially hundreds of millions of premature deaths result from inadequate mental health care and a decline in research. He continues to advocate for greater awareness, noting that the harms allegedly produced by psychedelics have been grossly exaggerated.
Prof. Nutt and Compass’ Dr. Guy Goodwin Discuss Access To Psychedelic Healthcare

Nutt remained on stage, and was joined for a panel discussion with Dr. Guy Goodwin, Compass Pathways’ Chief Medical Officer. The talk was moderated by Anne Philippi.
Guy discussed the company’s role in bringing psychedelics into mainstream health. Compass’ phase 3 study, recruiting almost one thousand patients, was completed earlier this year.
The company is currently on track to submit a dossier with the US FDA in mid-2026. Goodwin explained that the FDA is less affected by politics than before and has seen great consistency of performance and messaging.
Goodwin also discussed Lykos Therapeutics’ failure to pass FDA standards for MDMA therapy and said that data published by the FDA on the decision provides a learning opportunity.
After highlighting concerns for veteran welfare as driving forces for some pro-psychedelic policies, Nutt communicated the importance of reframing the cost of mental health treatments to reflect their value.
Nutt said that he sees overall optimism about the future of psychedelics in mainstream healthcare and the potential for significant improvements in mental health treatments. Key challenges for moving the needle on policy approvals include improving the public perception and media coverage of psychedelics, discussing a possible rebrand to “neuroplastogens.”
He also noted the importance of demonstrating the true cost-benefit of psychedelic treatments to the public and regulatory authorities.
Justin Smith-Ruiu: Psychedelics and the Reality of Experience

The conference’s main keynote was held by Justin Smith-Ruiu, professor of philosophy at Paris Cité University, who recently published “On Drugs,” a book that blends autobiography, intellectual history, and philosophical inquiry to explore the transformative impact of psychedelics on human consciousness and thought.
Smith-Ruiu discussed the potential of psychedelics for philosophical inquiry, offering engaging reflections on his personal experience with psilocybin, which helped him overcome a major depression and influenced his philosophical work.
He advocates for philosophers to consider the legitimacy of psychedelic experiences in their inquiry.
As part of a series of historical speculations, Smith-Ruiu said philosophers like Descartes and John Locke might have used psychedelics in the 17th century, as evidenced by the historical availability of psychedelic substances like fly agaric and ayahuasca.
He calls for academic philosophers to question their grounds for excluding psychedelic experiences from philosophical inquiry, challenging academic philosophy’s historic exclusions. He noted that between 1925 and 1975, no anglophone analytic philosopher openly admitted to having a psychedelic experience and argues that philosophers should rely on first-person intuition and seek out unusual experiences.
The philosopher questions why modern philosophy has neglected psychedelics as a significant data point in understanding perception and reality.
Smith-Ruiu argues that psychedelic experiences can clarify how we perceive reality and challenge entrenched assumptions about the mind and world. The phenomenological tradition in philosophy values inner experience as a means of accessing the basic structure of reality, he said. First-person reports of altered states can reveal hidden structures of selfhood, time, and meaning.
Panel Discussion: Psychedelics in the Real World —Where Are We Now?

Prof. Michael Lynskey, Researcher at Drug Science, moderated a panel which explored concepts of “real world” drug use, including medical, recreational, and informal use, with an emphasis on equitable access and diverse application, agreeing on the need for inclusive regulatory models to ensure safe, effective psychedelic use.
The panel included Prof. Celia Morgan, Professor of Psychopharmacology at the University of Exeter, Dr. Helena Aicher, Researcher and Psychotherapist at Universities of Basel & Zurich, Prof. Ranil Gunewardene, Director of Evolution MET, and Steve Rolles, Senior Policy Analyst at Transform Drug Policy Foundation
According to the panelists, 99.999% of psychedelic use occurs outside clinical settings and most recreational use is pleasure seeking, involving social settings like parties, raves, or casual gatherings.
Psychedelics demonstrate the first true innovation in mental health treatments in 35 years and have the potential to address treatment-resistant conditions like severe depression and trauma, showing promise for complex mental health cases.
As per real-world cases of legal psychedelic use, the panelists mentioned Australia as the first country to legalize psilocybin and MDMA for therapeutic use. Switzerland has had “exceptional permissions” for psychedelic therapy for over 10 years. Significant regulatory gaps exist between medical, recreational, and wellness-oriented psychedelic use.
In two years of psychedelic treatment in a major Sydney hospital, zero adverse outcomes reported and some patients require multiple treatment rounds (3-6 doses) for complex conditions.Psychedelics have a lower risk profile compared to some conventional medications like Clozapine, the panelists said.
However, challenges exist in the clinical research space. Most clinical trials have rigid exclusion criteria that prevent studying patients most likely to benefit and traditional rating scales often fail to capture the nuanced, qualitative improvements patients experience.
In the UK, there’s a growing underground therapy movement. There’s also increasing interest in community practice models for psychedelic use thought there’s limited formal availability for psychedelic treatment.
The panelists recommend to develop more flexible regulatory frameworks, create harm-reduction strategies, improve accessibility to psychedelic treatments and continue research into diverse application contexts.