Psyched Wellness has carried out a neurobehavioral study evaluating the safety and efficacy of its Amanita Muscaria extract – AME-1.
The result of the study shows that AME-1 alone or in combination with ethanol did not impair any learning or memory state, motor coordination, balance or altered behavioural activity.
The neurobehavioral study was to evaluate the efficacy and safety of Amanita muscaria extract (AME-1) alone, and in combination with ethanol, in a behavioural test battery including the Morris water maze (MWM), accelerating rotarod (RR) test, balance beam (BB) and forced swim tests (FST).
All of these tests are designed to look at behavioural despair, memory and learning, motor coordination, and maintaining balance.
Brian Tancowny, a scientific advisor for Psyched Wellness commented: “This milestone event further provides information in the toxicological assessment of AME-1.
“The results of this study further increases the knowledge in a scientific setting indicating no negative behavioural and neurological functional changes with the use of AME-1.”
The importance of this study in conjunction with the other toxicity studies is to provide scientific evidence for the efficacy and safety of AME-1. This study further understands the effects of AME-1 under a scientific methodology that reinforces a safe dose for human consumption.
KGK, a licensed CRO in Canada, completed the study.
Previous Psyched Wellness research has demonstrated that the extract holds a potential new functional property – inhibiting human mast cell activation – which could potentially work as a treatment for inflammatory skin conditions.
Additionally, in vivo findings have demonstrated that AME-1 has a potential priming effect on the immune system, allowing it to more efficiently respond to pathogens.
